Ontology highlight
ABSTRACT:
SUBMITTER: Al Musaimi O
PROVIDER: S-EPMC6571811 | biostudies-other | 2019 May
REPOSITORIES: biostudies-other
Al Musaimi Othman O El-Faham Ayman A Almarhoon Zainab Z Basso Alessandra A de la Torre Beatriz G BG Albericio Fernando F
Polymers 20190513 5
The "osmotic shock" phenomenon is the main thing that is responsible for morphological structure alteration, which can jeopardize the use of a polymer in a chemical process. This is extremely important in solid-phase peptide synthesis (SPPS), which is the method of choice for the preparation of these important biologically active compounds. Herein, we have used Hildebrand solubility parameters (δ) to investigate the influence of different ethers that are used in the precipitation step of the SPP ...[more]