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A novel magnet-based scratch method for standardisation of wound-healing assays.


ABSTRACT: A novel magnetic scratch method achieves repeatability, reproducibility and geometric control greater than pipette scratch assays and closely approximating the precision of cell exclusion assays while inducing the cell injury inherently necessary for wound healing assays. The magnetic scratch is affordable, easily implemented and standardisable and thus may contribute toward better comparability of data generated in different studies and laboratories.

SUBMITTER: Fenu M 

PROVIDER: S-EPMC6718675 | biostudies-other | 2019 Sep

REPOSITORIES: biostudies-other

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A novel magnet-based scratch method for standardisation of wound-healing assays.

Fenu M M   Bettermann T T   Vogl C C   Darwish-Miranda N N   Schramel J J   Jenner F F   Ribitsch I I  

Scientific reports 20190902 1


A novel magnetic scratch method achieves repeatability, reproducibility and geometric control greater than pipette scratch assays and closely approximating the precision of cell exclusion assays while inducing the cell injury inherently necessary for wound healing assays. The magnetic scratch is affordable, easily implemented and standardisable and thus may contribute toward better comparability of data generated in different studies and laboratories. ...[more]

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