Ontology highlight
ABSTRACT:
SUBMITTER: Liu W
PROVIDER: S-EPMC6721794 | biostudies-other | 2019 Aug
REPOSITORIES: biostudies-other
Liu Weiwei W Ganguly Anindya A Huang Jia J Wang Yijin Y Ni Jinfei D JD Gurav Adishthi S AS Aguilar Morris A MA Montell Craig C
eLife 20190812
Male courtship is provoked by perception of a potential mate. In addition, the likelihood and intensity of courtship are influenced by recent mating experience, which affects sexual drive. Using <i>Drosophila melanogaster</i>, we found that the homolog of mammalian neuropeptide Y, neuropeptide F (NPF), and a cluster of male-specific NPF (NPF<sup>M</sup>) neurons, regulate courtship through affecting courtship drive. Disrupting NPF signaling produces sexually hyperactive males, which are resistan ...[more]