Ontology highlight
ABSTRACT:
SUBMITTER: Rastinehad AR
PROVIDER: S-EPMC6744844 | biostudies-other | 2019 Sep
REPOSITORIES: biostudies-other
Rastinehad Ardeshir R AR Anastos Harry H Wajswol Ethan E Winoker Jared S JS Sfakianos John P JP Doppalapudi Sai K SK Carrick Michael R MR Knauer Cynthia J CJ Taouli Bachir B Lewis Sara C SC Tewari Ashutosh K AK Schwartz Jon A JA Canfield Steven E SE George Arvin K AK West Jennifer L JL Halas Naomi J NJ
Proceedings of the National Academy of Sciences of the United States of America 20190826 37
Biocompatible gold nanoparticles designed to absorb light at wavelengths of high tissue transparency have been of particular interest for biomedical applications. The ability of such nanoparticles to convert absorbed near-infrared light to heat and induce highly localized hyperthermia has been shown to be highly effective for photothermal cancer therapy, resulting in cell death and tumor remission in a multitude of preclinical animal models. Here we report the initial results of a clinical trial ...[more]