Ontology highlight
ABSTRACT:
SUBMITTER: Dominguez-Robles J
PROVIDER: S-EPMC6770814 | biostudies-other | 2019 Aug
REPOSITORIES: biostudies-other
Domínguez-Robles Juan J Stewart Sarah A SA Rendl Andreas A González Zoilo Z Donnelly Ryan F RF Larrañeta Eneko E
Biomolecules 20190828 9
Extensive efforts are being made to find alternative uses for lignin (LIG). In the present work the use of this biopolymer as excipient to prepare tablets was studied. For this purpose, LIG was combined with microcrystalline cellulose (MCC) and used as excipients to prepare directly compressed tablets containing a model drug, tetracycline (TC). The excipients contained different concentrations of LIG: 100%, 75%, 50%, 25% and 0% (<i>w</i>/<i>w</i>). Two different compression forces were used (two ...[more]