Ontology highlight
ABSTRACT:
SUBMITTER: Regmi S
PROVIDER: S-EPMC6794806 | biostudies-other | 2019 Oct
REPOSITORIES: biostudies-other
Regmi Shobha S Pathak Shiva S Thanh Tung Pham TP Nguyen Tiep Tien TT Sung Jong-Hyuk JH Yook Simmyung S Kim Jong Oh JO Yong Chul Soon CS Choi Inho I Doh Kyoung-Oh KO Park Pil-Hoon PH Park Jun-Beom JB Seo Yoojin Y Kim Bieong-Kil BK Lee Dong-Mok DM Moon Ik-Jae IJ Kim Hyung-Sik HS Jeong Jee-Heon JH
Stem cell research & therapy 20191016 1
<h4>Background</h4>Systemic inflammatory response syndrome (SIRS) is common in severe fulminant hepatic failure (FHF) and has a high mortality rate (20-50%) due to irreversible cerebral edema or sepsis. Stem cell-based treatment has emerged as a promising alternative therapeutic strategy to prolong the survival of patients suffering from FHF via the inhibition of SIRS due to their immunomodulatory effects.<h4>Methods</h4>3D spheroids of adipose-derived mesenchymal stem cells (3D-ADSC) were prepa ...[more]