Ontology highlight
ABSTRACT:
SUBMITTER: Nielsen MJ
PROVIDER: S-EPMC6796007 | biostudies-other | 2019 Oct
REPOSITORIES: biostudies-other
Nielsen Mette Juul MJ Villesen Ida Falk IF Gudmann Natasja Stæhr NS Leeming Diana Julie DJ Krag Aleksander A Karsdal Morten Asser MA Zimmermann Tim T Schuppan Detlef D
Scientific reports 20191016 1
Following liver transplantation (LT), 10-30% of patients develop recurrent cirrhosis (RC). There is an urgent need for predictive non-invasive markers for improved monitoring of these patients. Here we studied extracellular matrix biomarkers as predictors of RC after LT. Forty-seven LT patients were divided into groups of fast, intermediate or non-progressors towards RC (<1 year, 3-5 years or no advanced fibrosis >5 years after LT), assessed by follow-up liver biopsies. Markers of interstitial m ...[more]