Ontology highlight
ABSTRACT:
SUBMITTER: Attie O
PROVIDER: S-EPMC6816573 | biostudies-other | 2019
REPOSITORIES: biostudies-other
Attie Oliver O Sulkow Brian B Di Chong C Qiu Weigang W
PloS one 20191028 10
The Standard Genetic Code (SGC) is robust to mutational errors such that frequently occurring mutations minimally alter the physio-chemistry of amino acids. The apparent correlation between the evolutionary distances among codons and the physio-chemical distances among their cognate amino acids suggests an early co-diversification between the codons and amino acids. Here we formulated the co-minimization of evolutionary distances between codons and physio-chemical distances between amino acids a ...[more]