NBR1-mediated selective autophagy of ARF7 modulates root branching

ABSTRACT: Auxin dictates root architecture via the Auxin Response Factor (ARF) family of transcription factors, which control lateral root (LR) formation. In Arabidopsis, ARF7 regulates the specification of prebranch sites (PBS) generating LRs through gene expression oscillations and plays a pivotal role during LR initiation. Despite the importance of ARF7 in this process, there is a surprising lack of knowledge about how ARF7 turnover is regulated and how this impacts root architecture. Here, we show that ARF7 accumulates in autophagy mutants and is degraded through NBR1-dependent selective autophagy. We demonstrate that the previously reported rhythmic changes to ARF7 abundance in roots are modulated via autophagy and might occur in other tissues. Additionally, we show that the level of co-localiz

SUBMITTER: Dr. Elise, Nagel Ebstrup 

PROVIDER: S-SCDT-10_1038-S44319-024-00142-5 | biostudies-other |

REPOSITORIES: biostudies-other