Unknown

Dataset Information

0

UV-B photoreceptor UVR8 interacts with MYB73/MYB77 to regulate auxin responses and lateral root development


ABSTRACT: The UV-B photoreceptor UVR8 mediates multiple UV-B responses in plants, but the function of UVR8 in regulating root development has not previously been investigated. Here we show that UV-B light inhibits Arabidopsis lateral root growth in a UVR8-dependent manner. Monomeric UVR8 inhibits auxin responses in a tissue-autonomous manner and thereby regulates lateral root growth. Genome-wide gene expression analysis demonstrated that auxin and UV-B irradiation antagonistically regulate auxin-regulated gene expression. We further show that UVR8 physically interacts with MYB73/MYB77 (MYB DOMAIN PROTEIN 73/77) in a UV-B-dependent manner. UVR8 inhibits lateral root development via regulation of MYB73/MYB77. When activated by UV-B light, UVR8 localizes to the nucleus and inhibits the DNA-binding activities of MYB73/MYB77 and directly represses the transcription of their target auxin-responsive genes. Our results demonstrate that UV-B light and UVR8 are critical for both shoot morphogenesis and root development. The UV-B-dependent interaction of UVR8 and MYB73/MYB77 serves as an important module that integrates light and auxin signaling and represents a new UVR8 signaling mechanism in plants.

SUBMITTER: Yu Yang 

PROVIDER: S-SCDT-EMBOJ-2019-101928 | biostudies-other |

REPOSITORIES: biostudies-other

Similar Datasets

| S-EPMC6960441 | biostudies-literature
| S-EPMC7006904 | biostudies-literature
2021-04-11 | GSE162411 | GEO
| S-EPMC9043952 | biostudies-literature
| S-EPMC4352979 | biostudies-literature
| S-EPMC6800413 | biostudies-literature
| S-EPMC317103 | biostudies-literature
| S-EPMC3422273 | biostudies-literature
| S-EPMC6560076 | biostudies-literature
| S-EPMC5921505 | biostudies-literature