TOC1 clock protein phosphorylation controls complex formation with NF-YB/C to repress hypocotyl growth

ABSTRACT: Plant photoperiodic growth is coordinated by interactions between circadian clock and light signaling networks. How post-translational modifications of clock proteins affect these interactions to mediate rhythmic growth remains unclear. Here, we identify five phosphorylation sites in the Arabidopsis core clock protein TIMING OF CAB EXPRESSION 1 (TOC1) which when mutated to alanine eliminate detectable phosphorylation. The TOC1 phospho-mutant fails to fully rescue the clock, growth and flowering phenotypes of the toc1 mutant. Further, the TOC1 phospho-mutant shows advanced phase, a faster degradation rate, reduced interactions with PHYTOCHROME INTERACTING FACTOR3 (PIF3) and HISTONE DEACETYLASE 15 (HDA15), and poor binding at pre-dawn hypocotyl-growth-related genes (PHGs), leading to a net d

SUBMITTER: Dr. David, Edward Somers 

PROVIDER: S-SCDT-EMBOJ-2021-108684 | biostudies-other |

REPOSITORIES: biostudies-other