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Somatic Reference Standard for Cancer Sequencing

ABSTRACT:

In this study, we separately performed PCR-free whole genome sequencing on the paired tumor/normal melanoma COLO-829 and lymphoblastoid COLO-829BL cell lines across three separate institutions (TGen, Illumina, Genome Sciences Centre at the British Columbia Cancer Agency). We performed a meta-analysis of all data, in combination with the originally reported analysis of these cell lines by Pleasance et al., and report a somatic reference standard based on consensus events. This standard can be used as a reference for tumor/normal whole genome analyses.

PROVIDER: phs000932 | dbGaP |

SECONDARY ACCESSION(S): PRJNA287061PRJNA287062

REPOSITORIES: dbGaP

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