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Breast Cancer Genome Guided Therapy Study (BEAUTY)

ABSTRACT:

The Breast Cancer Genome Guided Therapy Study (BEAUTY) is a prospective neoadjuvant clinical study enrolling 140 women with Stage I-III breast cancer. The goals of this study were to 1) perform comprehensive sequencing of germline and tumor tissues (exome and RNA seq), 2) identify genomic alterations and perturbed pathways associated with response/resistance to standard chemotherapy, and 3) develop patient-derived xenograft (PDX) for testing of therapeutic regimens chosen on the basis of alterations identified by genetic sequencing.

PROVIDER: phs001050 | dbGaP |

SECONDARY ACCESSION(S): PRJNA306904PRJNA306903

REPOSITORIES: dbGaP

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	GapExchange_phs001050.v1.p1.xml	Xml
	dbGaPEx2.1.5.xsd	Other
	Study_Report.phs001050.BreastCancerGenGuidedTherapy.v1.p1.MULTI.pdf	Pdf
	manifest_phs001050.BreastCancerGenGuidedTherapy.v1.p1.c1.GRU.pdf	Pdf
	datadict_v2.xsl	Other

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