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Maternal folate and newborn DNA methylation meta-analysis

ABSTRACT:

Folic acid is routinely recommended for women trying to conceive to ensure proper fetal development. Mechanisms whereby periconceptional folate influences normal development and disease are poorly understood: epigenetics may be involved. This data represents meta-analysis results from a large epigenomics study to examine the association between maternal plasma folate during pregnancy and epigenome-wide DNA methylation using Illumina's HumanMethyl450 (450K) Beadchip in 1,996 newborns from two European cohorts. Results for all CpGs analyzed (419,905) are provided.

These data may be downloaded through the dbGaP Authorized Access portal under phg000701.v1.

PROVIDER: phs001059 | dbGaP |

SECONDARY ACCESSION(S): PRJNA308780PRJNA308779

REPOSITORIES: dbGaP

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	GapExchange_phs001059.v1.p1.xml	Xml
	dbGaPEx2.1.5.xsd	Other
	Study_Report.phs001059.MaternalPlasmaFolateNewborns.v1.p1.MULTI.pdf	Pdf
	manifest_phs001059.MaternalPlasmaFolateNewborns.v1.p1.c1.GRU.pdf	Pdf
	Release_Notes.phs001059.MaternalPlasmaFolateNewborns.v1.p1.MULTI.pdf	Pdf

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