Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Investigating Human Placentation and Pregnancy Using First Trimester Chorionic Villi

ABSTRACT:

Chorionic villus sampling (CVS) is routinely used for prenatal diagnosis of cytogenetic disorders, but also possesses great potential for studying placentation. To better understand villi biology, human placentation, and how these relate to pregnancy outcomes, we examined the morphology and transcriptomes of villi obtained via CVS from 10-14 weeks of pregnancy and correlated these with pregnancy attributes and clinical outcomes.

PROVIDER: phs001320 | dbGaP |

SECONDARY ACCESSION(S): PRJNA377796PRJNA377795

REPOSITORIES: dbGaP

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	GapExchange_phs001320.v1.p1.xml	Xml
	dbGaPEx2.1.5.xsd	Other
	phs001320.v1-Documents.zip	Other
	Study_Report.phs001320.PlacentaPregnancyChorionicVilli.v1.p1.MULTI.pdf	Pdf
	manifest_phs001320.PlacentaPregnancyChorionicVilli.v1.p1.c1.GRU-IRB-PUB-COL.pdf	Pdf

Items per page:

1 - 5 of 16

Similar Datasets

Genetic analysis, ultrasound phenotype, and pregnancy outcome of fetuses with Xp22.33 or Yp11.32 microdeletion

Project description:The phenotypes of Xp22.33 or Yp11.32 microdeletions containing short-stature homeobox (SHOX) gene have been extensively described in adults and children, however, few have been reported in prenatal fetuses. We analyzed the prenatal ultrasound phenotype and pregnancy outcomes of fetuses with Xp22.33 or Yp11.32 microdeletion containing SHOX gene to improve the understanding, diagnosis, and monitoring of the disease in the fetal period.

2023-01-24 | GSE223242 | GEO

Prenatal phenotypes and pregnancy outcomes of fetuses with 16p11.2 microdeletion/microduplication

Project description:Prenatal phenotypes and pregnancy outcomes of fetuses with 16p11.2 microdeletion/microduplication

| PRJNA1104671 | ENA

Chorionic villus sampling (CVS) microarray in preeclampsia

Project description:4 chorionic villus sampling specimens in pregnancies destined for preeclampsia and 8 matched controls were analyzed 36 genes were differentially expressed using J5 score and prediction modeling in caGEDA computer program Keywords: snap frozen, banked CVS specimens with known pregnancy outcomes revealed genes differentially expressed in preeclampsia pregnancies

2008-11-25 | GSE12767 | GEO

Prenatal phenotypes and pregnancy outcomes of fetuses with recurrent 1q21.1 microdeletions and microduplications

Project description:Prenatal phenotypes and pregnancy outcomes of fetuses with recurrent 1q21.1 microdeletions and microduplications

| PRJNA1004305 | ENA

Rare variation Micro-array raw data

Project description:A rare chromosome 20 with additional G-positive band was found during prenatal diagnosis. To identified the rare chromosome 20, standard cytogenetic and molecular cytogenetic analysis of the patients was performed. Array comparative genomic hybridization (aCGH) were performed to exclude genomic imbalance.

2016-06-27 | E-MTAB-4755 | biostudies-arrayexpress

Assessment of DNA methylation patterns related to femur bone morphology in vervet bone using the 850K array

Project description:The aim of this study was to characterize the genome-wide DNA methylation profiles of vervet femur trabecular bone samples (n=10) and identify how they relate to aspects of femur bone morphology. The Illumina Infinium MethylationEPIC Array was used to assess these genome-wide methylation patterns.

2020-03-14 | GSE103280 | GEO

Assessment of DNA methylation patterns related to femur bone morphology in macaque bone using the 850K array

Project description:The aim of this study was to characterize the genome-wide DNA methylation profiles of macaque femur trabecular bone samples (n=10) and identify how they relate to aspects of femur bone morphology. The Illumina Infinium MethylationEPIC Array was used to assess these genome-wide methylation patterns.

2020-03-14 | GSE103271 | GEO

Assessment of DNA methylation patterns related to femur bone morphology in marmoset bone using the 850K array

Project description:The aim of this study was to characterize the genome-wide DNA methylation profiles of marmoset femur trabecular bone samples (n=6) and identify how they relate to aspects of femur bone morphology. The Illumina Infinium MethylationEPIC Array was used to assess these genome-wide methylation patterns.

2020-03-15 | GSE103328 | GEO

Assessment of DNA methylation patterns related to femur bone morphology in baboon bone using the 850K array

Project description:The aim of this study was to characterize the genome-wide DNA methylation profiles of adult baboon femur trabecular bone samples (n=28) and identify how they relate to aspects of femur bone morphology. The Illumina Infinium MethylationEPIC Array was used to assess these genome-wide methylation patterns.

2020-03-14 | GSE103279 | GEO

Assessment of DNA methylation patterns related to femur bone morphology in nonhuman primate bone using the 850K array

Project description:The aim of this study was to characterize the genome-wide DNA methylation profiles of nonhuman primate trabecular bone samples (n=58), identify how they relate to aspects of femur bone morphology, and assess how these epigenetic patterns vary between taxa. The Illumina Infinium MethylationEPIC array was used to assess genome-wide methylation patterns.

2020-03-15 | GSE103287 | GEO