Gefitinib and Combination Chemotherapy in Treating Patients With Advanced or Recurrent Colorectal Cancer

ABSTRACT: Phase II trial to study the effectiveness of combining gefitinib with fluorouracil, leucovorin, and irinotecan in treating patients who have advanced or recurrent colorectal cancer. Biological therapies such as gefitinib may stop the growth of tumor cells by blocking the enzymes necessary for tumor cell growth. Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining gefitinib with fluorouracil, leucovorin, and irinotecan may kill more tumor cells

DISEASE(S): Stage Iv Colon Cancer,Adenocarcinoma,Stage Iv Rectal Cancer,Adenocarcinoma Of The Rectum,Signet Ring Adenocarcinoma Of The Rectum,Recurrent Colon Cancer,Rectal Neoplasms,Cystadenocarcinoma,Signet Ring Adenocarcinoma Of The Colon,Adenocarcinoma, Mucinous,Adenocarcinoma Of The Colon,Mucinous Adenocarcinoma Of The Colon,Recurrent Rectal Cancer,Colonic Neoplasms,Mucinous Adenocarcinoma Of The Rectum

PROVIDER: 2008706 | ecrin-mdr-crc |

REPOSITORIES: ECRIN MDR