Vaccine Therapy and Sargramostim With or Without Docetaxel in Treating Patients With Metastatic Lung Cancer or Metastatic Colorectal Cancer

ABSTRACT: This randomized phase I trial studies the side effects, best way to give, and best dose of docetaxel when given together with vaccine therapy and sargramostim in treating patients with metastatic lung cancer or metastatic colorectal cancer. Vaccines may make the body build an immune response to kill tumor cells. Colony-stimulating factors such as sargramostim increase the number of immune cells found in bone marrow and peripheral blood. Drugs used in chemotherapy, such as docetaxel, work in different ways to stop tumor cells from dividing so they stop growing or die. Combining vaccine therapy and sargramostim with docetaxel may kill more tumor cells.

DISEASE(S): Stage Iv Colon Cancer,Stage Iv Rectal Cancer,Small Cell Lung Carcinoma,Recurrent Non-small Cell Lung Cancer,Lung Neoplasms,Stage Iv Non-small Cell Lung Cancer,Recurrent Colon Cancer,Rectal Neoplasms,Carcinoma, Non-small-cell Lung,Recurrent Small Cell Lung Cancer,Recurrent Rectal Cancer,Colonic Neoplasms,Extensive Stage Small Cell Lung Cancer

PROVIDER: 2011218 | ecrin-mdr-crc |

REPOSITORIES: ECRIN MDR