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A Phase I Study of ECO-4601 in Patients With Advanced Cancer


ABSTRACT: The purpose of this study was to determine the maximum tolerated dose (MTD) and the recommended dose for future studies of ECO-4601 administered as a continuous IV infusion for 14 days with 7 days recovery (21 day cycle) in patients with histologically confirmed solid tumors (high grade glioma, colorectal, lung, breast, ovarian, pancreatic and prostate). This study was also designed to determine the clinical pharmacokinetic profile, safety of multiple cycles of administration, and document the antitumor activity of ECO-4601.

DISEASE(S): Ovarian Cancer,Lung Cancer,Glioma,Colorectal Cancer,Prostate Cancer,Pancreatic Cancer,Breast Cancer,Solid Tumors,Tumors

PROVIDER: 2029824 | ecrin-mdr-crc |

REPOSITORIES: ECRIN MDR

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