Bortezomib and Gemcitabine in Treating Older Patients With Advanced Solid Tumors

ABSTRACT: RATIONALE: Bortezomib may stop the growth of solid tumors by blocking some of the enzymes needed for cell growth and by blocking blood flow to the tumor. Drugs used in chemotherapy, such as gemcitabine, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Giving bortezomib together with gemcitabine may kill more tumor cells. PURPOSE: This phase I trial is studying the side effects and best dose of bortezomib and gemcitabine in treating older patients with advanced solid tumors.

DISEASE(S): Kidney Neoplasms,Lung Cancer,Sarcoma,Colorectal Cancer,Head And Neck Neoplasms,Pancreatic Cancer,Breast Cancer,Lung Neoplasms,Ovarian Cancer,Prostatic Neoplasms,Carcinoma, Renal Cell,Prostate Cancer,Head And Neck Cancer,Ovarian Neoplasms,Kidney Cancer,Pancreatic Neoplasms

PROVIDER: 2051011 | ecrin-mdr-crc |

REPOSITORIES: ECRIN MDR