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Radiofrequency Ablation in Resectable Colorectal Lung Metastasis

ABSTRACT: Lung metastasectomy is the only therapeutic option to provide a long-survival in patients with colorectal lung metastases. Recent studies have shown that radiofrequency (RF) ablation is a safe and useful therapeutic option for the treatment of unresectable lung metastases. In this phase-II trial, clinical utility of lung RF ablation will be evaluated in patients with resectable colorectal lung metastases.

DISEASE(S): Neoplasm Metastasis,Neoplasms, Second Primary,Lung Metastasis,Colorectal Cancer,Colorectal Neoplasms,Lung Neoplasms

PROVIDER: 2062849 | ecrin-mdr-crc |

REPOSITORIES: ECRIN MDR

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N7-Methylguanosine tRNA modification promotes hepatocellular carcinoma metastasis after insufficient radiofrequency ablation

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2022-11-20 | GSE199966 | GEO

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Project description:High-throughput RNA-seq analysis was performed using fresh residual CT26 tumors 3 days after incomplete radiofrequency abaltion (iRFA) as well as control tumors. We ound genes encoding damage-associated molecular patterns molecules (DAMPs), proinflammatory cytokines, chemokines, and genes associated with immunosuppression were overexpressed in the iRFA-treated tumor, indicating iRFA elicits inflammation and induces immunosuppression in residual tumors.

2019-10-02 | GSE138224 | GEO

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