Simultaneous Integrated Boost Preoperative Radiotherapy for Rectum Cancer
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ABSTRACT: The investigators propose a randomized non-inferiority trial that compares preoperative Fluoro Uracil (FU)-based chemoradiotherapy to radiotherapy with a simultaneous integrated boost. In patients with T3-4 rectal cancer, the latter approach is considered preferential with regard to toxicity and cost. The metabolic response of the tumor, as assessed by 18F-2-Fluoro-2-Deoxyglucose-Positron Emission tomography (18F-FDG PET) or PET-CT, will be used as a surrogate marker of cause specific outcome
DISEASE(S): Rectal Neoplasms,Colorectal Cancer,Colorectal Neoplasms,Rectal Cancer
PROVIDER: 2096816 | ecrin-mdr-crc |
REPOSITORIES: ECRIN MDR
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