Lenalidomide and Cetuximab in Treating Patients With Advanced Colorectal Cancer or Head and Neck Cancer

ABSTRACT: This phase I trial studies the side effects and the best dose of lenalidomide when given together with cetuximab in treating patients with colorectal cancer or head and neck cancer that has spread to other places in the body and usually cannot be cured or controlled with treatment. Biological therapies, such as lenalidomide, use substances made from living organisms that may stimulate the immune system in different ways and stop tumor cells from growing. Monoclonal antibodies, such as cetuximab, may block tumor growth in different ways by targeting certain cells. Giving lenalidomide together with cetuximab may be a better treatment for colorectal cancer or head and neck cancer.

DISEASE(S): Squamous Cell Carcinoma Metastatic In The Neck With Occult Primary,Stage Iv Hypopharyngeal Squamous Cell Carcinoma Ajcc V7,Carcinoma,Stage Ivc Lip And Oral Cavity Squamous Cell Carcinoma Ajcc V6 And V7,Recurrent Colon Carcinoma,Recurrent Metastatic Squamous Cell Carcinoma In The Neck With Occult Primary,Recurrent Rectal Carcinoma,Stage Ivb Major Salivary Gland Cancer Ajcc V7,Stage Ivb Oral Cavity Cancer Ajcc V6 And V7,Stage Ivc Oropharyngeal Squamous Cell Carcinoma Ajcc V7,Stage Iv Nasopharyngeal Keratinizing Squamous Cell Carcinoma Ajcc V7,Stage Iva Oropharyngeal Squamous Cell Carcinoma Ajcc V7,Stage Iva Laryngeal Verrucous Carcinoma Ajcc V7,Stage Ivc Oral Cavity Cancer Ajcc V6 And V7,Recurrent Salivary Gland Carcinoma,Stage Ivc Laryngeal Verrucous Carcinoma Ajcc V7,Salivary Gland Neoplasms,Recurrent Hypopharyngeal Squamous Cell Carcinoma,Recurrent Oropharyngeal Squamous Cell Carcinoma,Stage Ivc Major Salivary Gland Cancer Ajcc V7,Stage Ivb Colon Cancer Ajcc V7,Carcinoma, Squamous Cell,Squamous Cell Carcinoma Of Head And Neck,Stage Iva Lip And Oral Cavity Squamous Cell Carcinoma Ajcc V6 And V7,Rectal Neoplasms,Recurrent Oral Cavity Verrucous Carcinoma,Stage Ivb Rectal Cancer Ajcc V7,Stage Ivb Oropharyngeal Squamous Cell Carcinoma Ajcc V7,Stage Ivb Laryngeal Verrucous Carcinoma Ajcc V7,Stage Iva Colon Cancer Ajcc V7,Stage Ivb Nasal Cavity And Paranasal Sinus Squamous Cell Carcinoma Ajcc V7,Stage Iva Nasal Cavity And Paranasal Sinus Squamous Cell Carcinoma Ajcc V7,Stage Ivb Lip And Oral Cavity Squamous Cell Carcinoma Ajcc V6 And V7,Salivary Gland Squamous Cell Carcinoma,Stage Ivb Laryngeal Squamous Cell Carcinoma Ajcc V7,Stage Ivc Laryngeal Squamous Cell Carcinoma Ajcc V7,Stage Iva Major Salivary Gland Cancer Ajcc V7,Stage Iva Laryngeal Squamous Cell Carcinoma Ajcc V7,Recurrent Nasal Cavity And Paranasal Sinus Squamous Cell Carcinoma,Stage Iva Oral Cavity Cancer Ajcc V6 And V7,Stage Ivc Nasal Cavity And Paranasal Sinus Squamous Cell Carcinoma Ajcc V7,Recurrent Laryngeal Verrucous Carcinoma,Recurrent Nasopharyngeal Keratinizing Squamous Cell Carcinoma,Mouth Neoplasms,Recurrent Laryngeal Squamous Cell Carcinoma,Recurrent Lip And Oral Cavity Squamous Cell Carcinoma,Stage Iva Rectal Cancer Ajcc V7,Tongue Carcinoma,Carcinoma, Verrucous,Colonic Neoplasms

PROVIDER: 2099116 | ecrin-mdr-crc |

REPOSITORIES: ECRIN MDR