Deferasirox in Treating Iron Overload Caused By Blood Transfusions in Patients With Hematologic Malignancies

ABSTRACT: RATIONALE: Deferasirox may remove excess iron from the body caused by blood transfusions. PURPOSE: This clinical trial studies deferasirox in treating iron overload caused by blood transfusions in patients with hematologic malignancies.

DISEASE(S): Adult Grade Iii Lymphomatoid Granulomatosis,Lymphoma, Large-cell, Immunoblastic,Stage I Adult Diffuse Small Cleaved Cell Lymphoma,Stage Iv Adult Diffuse Mixed Cell Lymphoma,Stage Iv Adult Immunoblastic Large Cell Lymphoma,Recurrent Grade 1 Follicular Lymphoma,Myelodysplastic/myeloproliferative Neoplasm, Unclassifiable,Stage I Small Lymphocytic Lymphoma,Contiguous Stage Ii Adult Diffuse Small Cleaved Cell Lymphoma,Contiguous Stage Ii Marginal Zone Lymphoma,Mycosis Fungoides,Stage Iv Adult Lymphoblastic Lymphoma,Stage Iii Adult Burkitt Lymphoma,Previously Treated Myelodysplastic Syndromes,Stage I Grade 1 Follicular Lymphoma,Stage Ii Cutaneous T-cell Non-hodgkin Lymphoma,Recurrent Adult Burkitt Lymphoma,Leukemia, T-cell,Lymphomatoid Granulomatosis,De Novo Myelodysplastic Syndromes,Lymphoma, T-cell, Peripheral,Stage Iv Mycosis Fungoides/sezary Syndrome,Preleukemia,Lymphoma, B-cell, Marginal Zone,Stage I Adult Immunoblastic Large Cell Lymphoma,Nodal Marginal Zone B-cell Lymphoma,Noncontiguous Stage Ii Grade 3 Follicular Lymphoma,Recurrent Small Lymphocytic Lymphoma,Adult Acute Myeloid Leukemia With Inv(16)(p13;q22),Lymphoma, T-cell, Cutaneous,Adult Acute Myeloid Leukemia With Del(5q),Stage Iv Adult Burkitt Lymphoma,Contiguous Stage Ii Grade 3 Follicular Lymphoma,Stage I Adult Diffuse Large Cell Lymphoma,Stage Iii Adult T-cell Leukemia/lymphoma,Stage Iii Adult Diffuse Large Cell Lymphoma,Lymphoma, Follicular,Waldenstrom Macroglobulinemia,Iron Overload,Recurrent Mantle Cell Lymphoma,Stage Iii Cutaneous T-cell Non-hodgkin Lymphoma,Contiguous Stage Ii Grade 1 Follicular Lymphoma,Leukemia,Hodgkin Disease,Recurrent Adult Hodgkin Lymphoma,Mycoses,Contiguous Stage Ii Adult Diffuse Large Cell Lymphoma,Recurrent Adult Lymphoblastic Lymphoma,Secondary Myelofibrosis,Leukemia, Myeloid, Acute,Stage Ii Multiple Myeloma,Contiguous Stage Ii Adult Diffuse Mixed Cell Lymphoma,Testicular Lymphoma,Stage I Grade 3 Follicular Lymphoma,Noncontiguous Stage Ii Mantle Cell Lymphoma,Contiguous Stage Ii Grade 2 Follicular Lymphoma,Untreated Adult Acute Myeloid Leukemia,Lymphoma, T-cell,Myelodysplastic Syndromes,Noncontiguous Stage Ii Adult Diffuse Mixed Cell Lymphoma,Stage Iv Grade 3 Follicular Lymphoma,Recurrent Adult Acute Myeloid Leukemia,Leukemia, Myeloid,Immunoblastic Lymphadenopathy,Noncontiguous Stage Ii Marginal Zone Lymphoma,Stage Iii Multiple Myeloma,Histiocytosis,Refractory Multiple Myeloma,Noncontiguous Stage Ii Small Lymphocytic Lymphoma,Anemia, Refractory,Recurrent Adult Diffuse Mixed Cell Lymphoma,Myeloid/nk-cell Acute Leukemia,Stage Iv Grade 2 Follicular Lymphoma,Contiguous Stage Ii Small Lymphocytic Lymphoma,Recurrent Adult T-cell Leukemia/lymphoma,Stage Ii Adult Hodgkin Lymphoma,Stage Iv Cutaneous T-cell Non-hodgkin Lymphoma,Contiguous Stage Ii Mantle Cell Lymphoma,Stage I Grade 2 Follicular Lymphoma,Noncontiguous Stage Ii Adult Diffuse Large Cell Lymphoma,Lymphoma, Non-hodgkin,Recurrent Adult Diffuse Large Cell Lymphoma,Histiocytosis, Langerhans-cell,Lymphoma, B-cell,Stage I Adult T-cell Leukemia/lymphoma,Extranodal Marginal Zone B-cell Lymphoma Of Mucosa-associated Lymphoid Tissue,Lymphoma, Large B-cell, Diffuse,Contiguous Stage Ii Adult Lymphoblastic Lymphoma,Stage Iv Adult T-cell Leukemia/lymphoma,Myeloproliferative Disorders,Stage Iv Adult Diffuse Large Cell Lymphoma,Myelodysplastic-myeloproliferative Diseases,Contiguous Stage Ii Adult Immunoblastic Large Cell Lymphoma,Adult Langerhans Cell Histiocytosis,Noncontiguous Stage Ii Adult Immunoblastic Large Cell Lymphoma,Small Intestine Lymphoma,Sezary Syndrome,Neoplasm Metastasis,Adult Nasal Type Extranodal Nk/t-cell Lymphoma,Untreated Adult Acute Lymphoblastic Leukemia,Myelodysplastic Syndrome With Isolated Del(5q),Secondary Acute Myeloid Leukemia,Splenic Marginal Zone Lymphoma,Stage I Marginal Zone Lymphoma,Lymphoma, Mantle-cell,Noncontiguous Stage Ii Adult Burkitt Lymphoma,Leukemia-lymphoma, Adult T-cell,Adult Acute Myeloid Leukemia In Remission,Stage Iii Adult Diffuse Small Cleaved Cell Lymphoma,Recurrent Adult Immunoblastic Large Cell Lymphoma,Multiple Myeloma,Stage Iv Grade 1 Follicular Lymphoma,Stage Iv Mantle Cell Lymphoma,Stage I Adult Hodgkin Lymphoma,Leukemia, Mast-cell,Stage I Adult Diffuse Mixed Cell Lymphoma,Contiguous Stage Ii Adult Burkitt Lymphoma,Lymphoma, Extranodal Nk-t-cell,Stage Ii Adult T-cell Leukemia/lymphoma,Plasmablastic Lymphoma,Stage I Cutaneous T-cell Non-hodgkin Lymphoma,Stage Ii Mycosis Fungoides/sezary Syndrome,Burkitt Lymphoma,Stage I Mantle Cell Lymphoma,Stage Iii Mycosis Fungoides/sezary Syndrome,Recurrent Adult Diffuse Small Cleaved Cell Lymphoma,Stage Iii Adult Immunoblastic Large Cell Lymphoma,Stage Iii Grade 1 Follicular Lymphoma,Acute Undifferentiated Leukemia,Stage Iii Marginal Zone Lymphoma,Adult Acute Myeloid Leukemia With T(8;21)(q22;q22),Stage I Multiple Myeloma,Stage Iii Adult Diffuse Mixed Cell Lymphoma,Adult Acute Myeloid Leukemia With 11q23 (mll) Abnormalities,Recurrent Marginal Zone Lymphoma,Recurrent Adult Grade Iii Lymphomatoid Granulomatosis,Stage I Mycosis Fungoides/sezary Syndrome,Leukemia, Lymphocytic, Chronic, B-cell,Intraocular Lymphoma,Stage I Adult Lymphoblastic Lymphoma,Neoplasms, Plasma Cell,Noncontiguous Stage Ii Adult Diffuse Small Cleaved Cell Lymphoma,Recurrent Adult Acute Lymphoblastic Leukemia,Recurrent Grade 3 Follicular Lymphoma,Primary Myelofibrosis,Refractory Anemia,Stage Iii Adult Hodgkin Lymphoma,Stage Iii Grade 2 Follicular Lymphoma,Adult Acute Lymphoblastic Leukemia In Remission,Angioimmunoblastic T-cell Lymphoma,Noncutaneous Extranodal Lymphoma,Stage Iv Marginal Zone Lymphoma,Lymphoma, Large-cell, Anaplastic,Stage Iv Adult Hodgkin Lymphoma,Stage Iii Mantle Cell Lymphoma,Noncontiguous Stage Ii Grade 2 Follicular Lymphoma,Stage Iii Grade 3 Follicular Lymphoma,Adult Acute Myeloid Leukemia With T(16;16)(p13;q22),Hepatosplenic T-cell Lymphoma,Leukemia, Lymphoid,Stage Iv Adult Diffuse Small Cleaved Cell Lymphoma,Precursor Cell Lymphoblastic Leukemia-lymphoma,Noncontiguous Stage Ii Grade 1 Follicular Lymphoma,Recurrent Cutaneous T-cell Non-hodgkin Lymphoma,Noncontiguous Stage Ii Adult Lymphoblastic Lymphoma,Stage Iv Small Lymphocytic Lymphoma,Lymphoma,Recurrent Mycosis Fungoides/sezary Syndrome,Anaplastic Large Cell Lymphoma,Stage Iii Small Lymphocytic Lymphoma,Recurrent Grade 2 Follicular Lymphoma,Adult Acute Myeloid Leukemia With T(15;17)(q22;q12),Peripheral T-cell Lymphoma,Stage Iii Adult Lymphoblastic Lymphoma,Mast Cell Leukemia,Cutaneous B-cell Non-hodgkin Lymphoma,Stage I Adult Burkitt Lymphoma

PROVIDER: 2100588 | ecrin-mdr-crc |

REPOSITORIES: ECRIN MDR