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Liquid biopsies in patients with peritoneal metastases of colorectal cancer.

ABSTRACT: Interventions: This is an observational cohort study to assess the correlation between ctDNA and cytoreductive surgery. No interventions are performed. Treatment and follow-up of patients will not be influenced by ctDNA results. Two additional viles of blood (2*9mL Streck) are taken before (on the day of HIPEC surgery) and after cytoreductive surgery and HIPEC (2-4 weeks after HIPEC surgery). Primary outcome(s): Plasma levels of ctDNA preoperatively. Study Design: N/A: single arm study, Single blinded (masking used), N/A , unknown, Other

DISEASE(S): Peritoneal Metastases (pm), Colorectal Cancer (crc), Cytoreductive Surgery And Hyperthermic Intraperitoneal Chemotherapy (hipec), Liquid Biopsy, Circulating Tumor Dna (ctdna)dutch: Peritoneale Metastasen (pm), Colorectaal Carcinoom (crc), Cytoreductie En Hypertherme Intraperitoneale Chemotherapie (hipec), Liquid Biopsy, Circulerend Tumor Dna (ctdna)

PROVIDER: 21377 | ecrin-mdr-crc |

REPOSITORIES: ECRIN MDR

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Exploiting a subtype-specific mitochondrial vulnerability for successful treatment of colorectal peritoneal metastases

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