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Ph 1-2 Study ADI-PEG 20 Plus FOLFOX in Subjects With Advanced GI Malignancies Focusing on Hepatocellular Carcinoma

ABSTRACT: Phase 1: Assessment of safety and tolerability of ADI-PEG 20 in combination with folinic acid (leucovorin), fluorouracil and oxaliplatin (FOLFOX) in advanced GI malignancies. Phase 2: Assessment of the objective response rate (ORR), measured by RECIST 1.1 criteria as assessed by blinded independent central review (BICR).

DISEASE(S): Carcinoma,Advanced Gastrointestinal (gi) Malignancies,Gastric Cancer,Colorectal Cancer,Carcinoma, Hepatocellular,Advanced Hepatocellular Carcinoma (hcc)in The Third Line Or Later Setting,Carcinoma Hepatocellular,Neoplasms,Hepatocellular Carcinoma

PROVIDER: 2163812 | ecrin-mdr-crc |

REPOSITORIES: ECRIN MDR

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