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Irinotecan-Eluting Beads in Treating Patients With Refractory Metastatic Colon or Rectal Cancer That Has Spread to the Liver


ABSTRACT: This phase I trial studies the side effects and best dose of irinotecan-eluting beads in treating patients with colon or rectal cancer that has spread to the liver and does not respond to treatment with standard therapy. Irinotecan-eluting beads are tiny beads that have been loaded with irinotecan hydrochloride, a chemotherapy drug. Drugs used in chemotherapy, such as irinotecan hydrochloride, work in different ways to stop the growth of tumor cells, either by killing the cells or stopping them from dividing. This treatment delivers the chemotherapy directly to the tumor area inside the liver instead of to the whole body as with systemic delivery of the drug. Irinotecan-eluting beads may work better that standard chemotherapy in treating patients with colon or rectal cancer that has spread to the liver.

DISEASE(S): Adenocarcinoma,Stage Ivb Colon Cancer,Signet Ring Adenocarcinoma Of The Rectum,Recurrent Colon Cancer,Rectal Neoplasms,Cystadenocarcinoma,Liver Metastases,Stage Iva Rectal Cancer,Signet Ring Adenocarcinoma Of The Colon,Stage Ivb Rectal Cancer,Adenocarcinoma, Mucinous,Mucinous Adenocarcinoma Of The Colon,Recurrent Rectal Cancer,Colonic Neoplasms,Stage Iva Colon Cancer,Mucinous Adenocarcinoma Of The Rectum

PROVIDER: 2164492 | ecrin-mdr-crc |

REPOSITORIES: ECRIN MDR

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