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Adjuvant HIPEC in High Risk Colon Cancer

ABSTRACT: This study aims to determine the oncological effectiveness of adjuvant HIPEC, using intraperitoneal oxaliplatin with concomitant i.v. 5-FU/LV, following a curative resection of a T4 or intra-abdominally perforated Colon cancer in preventing the development of peritoneal carcinomatosis in addition to the standard adjuvant systemic treatment. Hypothesis: The hypothesis is that adjuvant HIPEC preceding routine adjuvant systemic therapy using i.p. oxaliplatin with concomitant i.v. 5-FU/LV following a curative resection of a T4 or intra-abdominally perforated colon cancer reduces the development of peritoneal carcinomatosis in comparison to standard adjuvant systemic treatment alone.

DISEASE(S): Peritoneal Neoplasms,Adjuvante Hypertherme Intraperitoneale Chemotherapie Bij Patiënten Met Een Colon Carcinoom En Een Hoog Risico Op Peritonitis Carcinomatosa; De Multicenter Gerandomiseerde Colopec Studie,Adjuvant Hyperthermic Intraperitoneal Chemotherapy In Patients With Colon Cancer At High Risk Of Peritoneal Carcinomatosis; The Colopec Randomized Multicenter Trial,Colorectal Neoplasms,Neoplasms

PROVIDER: 2173696 | ecrin-mdr-crc |

REPOSITORIES: ECRIN MDR

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