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Study of CM-24 (MK-6018) Alone and In Combination With Pembrolizumab (MK-3475) in Participants With Selected Advanced or Recurrent Malignancies (MK-6018-001)

ABSTRACT: The purpose of this study is to evaluate the safety and tolerability of humanized IgG4 (kappa) isotype monoclonal antibody against CEACAM1 (CM-24 [MK-6018]), administered intravenously as monotherapy and in combination with Pembrolizumab (MK-3475), in participants with selected advanced or recurrent malignancies. Escalating multiple doses will be evaluated to determine the recommended dose for Phase 2 clinical studies.

DISEASE(S): Ovarian Cancer,Non-small Cell Lung Carcinoma (nsclc),Melanoma,Colorectal Cancer,Gastric Cancer,Bladder Cancer,Carcinoma, Non-small-cell Lung,Cancer

PROVIDER: 2182574 | ecrin-mdr-crc |

REPOSITORIES: ECRIN MDR

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