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A Study Of Avelumab In Combination With Other Cancer Immunotherapies In Advanced Malignancies (JAVELIN Medley)

ABSTRACT: This is a Phase 1b/2 dose-optimization study to evaluate safety, pharmacokinetics, pharmacodynamics, and preliminary antitumor activity of avelumab (MSB0010718C) in combination with other cancer immunotherapies in patients with locally advanced or metastatic solid tumors. The primary purpose is to assess the safety and early signs of efficacy of various avelumab combinations with other cancer immunotherapies, optimizing dosing regimens as appropriate, in a limited series of indications.

DISEASE(S): Melanoma,Gastric Cancer,Bladder Cancer,Advanced Cancer,Non-small Cell Lung Cancer (nsclc),Neoplasms,Locally Advanced Or Metastatic Solid Tumors [eg, Non-small Cell Lung Cancer (nsclc), Melanoma, And Squamous Cell Carcinoma Of The Head And Neck (scchn)] Triple-negative Breast Cancer (tnbc), Or Colorectal Cancer (crc)].

PROVIDER: 2198495 | ecrin-mdr-crc |

REPOSITORIES: ECRIN MDR

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