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Non-Surgical Management of Attenuated and Deleterious (Classical) Familial Adenomatous Polyposis: A Long-term Surveillance Program

ABSTRACT: The primary objective of this chart review study is to evaluate the outcomes of subjects with Attenuated Familial Adenomatous Polyposis (AFAP) and Deleterious Familial Adenomatous Polyposis (FAP) who have not undergone surgical resection of the colon. A secondary objective of this study is to compare 1) the colonoscopic and pathology histories including history of ampullary adenoma in the duodenum over family generations, 2) the use of chemopreventive medications, and 3) clinical features of subjects who pursued prophylactic surgical resection of the colon with those that have elected to continue routine colonoscopic surveillance in an effort to better characterize factors (e.g. polyp burden, ampullary adenoma and level of dysplasia, etc) which may influence management decisions.

DISEASE(S): Attenuated Familial Adenomatous Polyposis,Adenomatous Polyposis Coli,Colorectal Neoplasms,Nasopharyngeal Neoplasms,Deleterious Familial Adenomatous Polyposis

PROVIDER: 2213281 | ecrin-mdr-crc |

REPOSITORIES: ECRIN MDR

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