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Palbociclib With Cisplatin or Carboplatin in Advanced Solid Tumors

ABSTRACT: This phase I trial studies the side effects and best dose of palbociclib with cisplatin or carboplatin in treating patients with solid tumors that have spread to other places and usually cannot be cured or controlled with treatment. Palbociclib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Drugs used in chemotherapy, such as cisplatin and carboplatin, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Giving palbociclib with cisplatin or carboplatin may help stop tumor growth in patients with advanced solid tumors.

DISEASE(S): Stage Iva Pancreatic Cancer,Stage Iiib Non-small Cell Lung Cancer,Sarcoma,Stage Iv Breast Cancer,Stage Iiia Breast Cancer,Stage Iii Pancreatic Cancer,Colorectal Cancer,Stage Iiib Breast Cancer,Bladder Cancer,Breast Neoplasms,Lung Neoplasms,Stage Iiic Breast Cancer,Stage Iv Non-small Cell Lung Cancer,Ovarian Cancer,Solid Neoplasm,Stage Iiia Non-small Cell Lung Cancer,Cancer Of Unknown Primary,Carcinoma, Non-small-cell Lung,Head And Neck Cancer,Stage Ivb Pancreatic Cancer,Pancreatic Neoplasms

PROVIDER: 2224744 | ecrin-mdr-crc |

REPOSITORIES: ECRIN MDR

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