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FOLFIRI + Panitumumab First-line Treatment in Elderly Patients With Unresectable Metastatic Colorectal Cancer, RAS/BRAF Wild-type and Good Performance Status

ABSTRACT: To estimate progression-free survival at one year in elderly patients with RAS/BRAF wild-type unresectable mCRC and good performance status treated with FOLFIRI + panitumumab as first-line therapy. The clinical hypothesis of this study is that the combination of panitumumab and FOLFIRI is a good treatment option in elderly patients with good performance status and RAS/BRAF wild-type unresectable mCRC. Another purpose of this clinical trial is to determine the RAS/BRAF mutation status in liquid biopsies at baseline and at the time of disease progression.

DISEASE(S): Colorectal Carcinoma,Metastatic Colorectal Cancer,Neoplasm Metastasis,First-line Treatment In Elderly Patients With Ras/braf Wild-type Unresectable Metastatic Colorectal Cancer And Good Performance Status,Tratamiento De Primera Línea En Pacientes Ancianos Con Cáncer Colorrectal Metastásico No Resecable, Ras/braf No Mutado Y Buen Estado Funcional,Colorectal Neoplasms,Colorectal Cancer Metastatic,Neoplasms

PROVIDER: 2243561 | ecrin-mdr-crc |

REPOSITORIES: ECRIN MDR

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