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A Study of Personalized Neoantigen Cancer Vaccines


ABSTRACT: The purpose of this study is 1) to evaluate the feasibility of manufacturing a patient-specific neoantigen cancer vaccine, which involves predicting the patient’s neoantigens and generating a vaccine that encodes the predicted neoantigens; and, 2) to identify and select patients who may be eligible for a shared neoantigen cancer vaccine where their tumor contains a specific shared mutation and who have the correct HLA allele capable of presenting the neoantigen derived from the tumor-specific mutation.

DISEASE(S): Adenocarcinoma,Gastroesophageal Adenocarcinoma,Colorectal Cancer,Non Small Cell Lung Cancer,Urothelial Carcinoma,Pancreatic Ductal Adenocarcinoma

PROVIDER: 2293590 | ecrin-mdr-crc |

REPOSITORIES: ECRIN MDR

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