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Chromogranin A as Blood Marker in Cancer Patients


ABSTRACT: Gastroentero-pancreatic neuroendocrine tumors (GEP-NETs) are a heterogenous group of neoplasms that arise from enterochromaffin cells of the gastrointestinal (GI) tract and pancreas. They account for 50-70% of all incident NETs. Due to the lack of symptoms in the early stage of disease and the frequency of nonspecific GI symptoms, GEP-NETs are difficult to diagnose. Identification of effective biomarkers (such as Chromogranin A) to improve GEP-NET diagnosis, as well as to assess treatment efficacy, relapse and prognosis, is important for improving outcomes for patients with GEP-NETs. The purpose of this study is to validate the performance of Brahms (BRAHMS) Chromogranin A II Kryptor (KRYPTOR) assay to monitor the course of disease in patients with well-defined GEP-NETs.

DISEASE(S): Gastric Neoplasms,Colorectal Neoplasms,Pancreatic Neoplasms,Stomach Neoplasms,Intestinal Neoplasms,Neoplasms,Small Intestinal Neoplasms

PROVIDER: 2295412 | ecrin-mdr-crc |

REPOSITORIES: ECRIN MDR

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