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Local Immunomodulation After Radiofrequency of Unresectable Colorectal Liver Metastases

ABSTRACT: The main objective of this trial is to determine feasibility and tolerance of the human body to RFA associated with local immunomodulation carried out using a thermoreversible hydrogel combined with 2 immunomodulators, GMCSF and Mifamurtide. The main endpoint of the study is the feasibility, the frequency and the nature of per and post-operative adverse events of the in situ injection of an immunomodulatory hydrogel after radiofrequency of unresectable colorectal liver metastases. The secondary objective is one-year progression free survival rate.

DISEASE(S): Neoplasm Metastasis,Colorectal Cancer,Unresectable Colorectal Liver Metastases,Liver Neoplasms

PROVIDER: 2314216 | ecrin-mdr-crc |

REPOSITORIES: ECRIN MDR

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