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Dose Escalation Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of QBS10072S


ABSTRACT: This is a multi-center, open-label, dose escalation study to determine the safety, tolerability, pharmacokinetics, pharmacodynamics, and maximum tolerated dose (MTD) of QBS10072S in patients with advanced or metastatic cancers with high LAT1 expression. The MTD of QBS10072S will be confirmed in patients with relapsed or refractory grade 4 astrocytoma.

DISEASE(S): Lung Cancer,Thymoma,Tongue Cancer,Glioblastoma,Colorectal Cancer,Mesothelioma,Liver Cancer,Brain Neoplasms,Ovarian Cancer,Esophagus Cancer,Neoplasm Metastasis,Esophageal Neoplasms,Vomiting,Pleural Mesothelioma,Thymic Carcinoma,Gastric Cancer,Brain Cancer,Brain Metastases,Cholangiocarcinoma,Astrocytoma,Seizures,Urinary Tract Cancer,Sarcoma,Cervical Cancer,Melanoma,Bladder Cancer,Pancreatic Cancer,Breast Cancer,Tongue Neoplasms,Prostate Cancer,Head And Neck Cancer,Kidney Cancer,Urologic Neoplasms,Cancer

PROVIDER: 2342491 | ecrin-mdr-crc |

REPOSITORIES: ECRIN MDR

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