CAR-macrophages for the Treatment of HER2 Overexpressing Solid Tumors
Ontology highlight
ABSTRACT:
DISEASE(S): Adenocarcinoma,Endometrial Cancer,Her-2 Gene Amplification,Carcinoma,Carcinoma, Transitional Cell,Breast Neoplasm,Biliary Tract Neoplasms,Her-2 Protein Overexpression,Colorectal Cancer,Her2-positive Gastric Cancer,Head And Neck Neoplasms,Endometrial Neoplasms,Breast Neoplasms,Lung Neoplasms,Neoplasms,Her2-positive,Prostatic Neoplasms,Carcinoma, Small Cell,Bile Duct Cancer,Carcinoma, Non-small-cell Lung,Her2-positive Breast Cancer,Ovarian Neoplasms,Lung Cancer, Non-small-cell,Stomach Neoplasms,Malignant Neoplasms,Small Cell Lung Carcinoma,Advanced Cancer,Bladder Cancer,Pancreatic Cancer,Inflammatory Breast Cancer,Breast Cancer,Carcinoma, Squamous Cell,Her2-positive Solid Tumors,Esophagogastric Junction Neoplasms,Lung Cancer, Small Cell,Biliary Tract Cancer,Carcinoma, Ductal,Carcinoma, Ovarian Epithelial,Bile Duct Neoplasms,Prostate Cancer,Inflammatory Breast Neoplasms,Carcinoma, Hepatocellular,Head And Neck Cancer,Cancer,Carcinoma, Squamous
PROVIDER: 2360169 | ecrin-mdr-crc |
REPOSITORIES: ECRIN MDR
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Project description:This study is a first in human Phase 1 study that involves patients with a type of cancer called HER2 (Human Epidermal Growth Factor Receptor 2) positive cancer.
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The study is looking at combining these two treatments together, because we think that the combination of treatments will work better than each treatment alone. We also hope to learn the best dose level of the treatments and whether or not it is safe to use them together.
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