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Efficacy of Tislelizumab and Spartalizumab Across Multiple Cancer-types in Patients With PD1-high mRNA Expressing Tumors

ABSTRACT: This is an open-label, parallel group, non-randomized, multicenter phase II study to evaluate the efficacy of spartalizumab (cohorts 1 and 2) and tislelizumab (cohort 3) in monotherapy in patients with PD1-high-expressing tumors.

DISEASE(S): Adenocarcinoma,Colorectal Adenocarcinoma,Thyroid Neoplasms,Pancreatic Adenocarcinoma,Carcinoma,Prostate Adenocarcinoma,Anal Carcinoma,Triple Negative Breast Neoplasms,Small Cell Lung Cancer,Squamous Esophageal Carcinoma,Adenocarcinoma, Clear Cell,Cervical Carcinoma,Mesothelioma,Triple Negative Breast Cancer,Urothelial Carcinoma,Msi-h Colorectal Cancer,Breast Neoplasms,Hormone Receptor Positive / Her2-negative Breast Cancer,Stomach Adenocarcinoma,Esophageal Neoplasms,Thyroid Carcinoma,Epithelial Ovarian Cancer,Carcinoma Of Unknown Primary,Her2-positive Breast Cancer,Head And Neck Squamous Cell Carcinoma,Uterine Carcinosarcoma,Cholangiocarcinoma,Hepatocellular Carcinoma,Adenomyoepithelioma,Lung Adenocarcinoma,Sarcoma,Uveal Melanoma,Other Histology,Carcinosarcoma,Melanoma,Kidney Clear Cell Carcinoma,Small Cell Lung Carcinoma,Lung Adenocarcinoma Egfr-mutated/ Alk Traslocation,Uterine Adenocarcinoma,Carcinoma, Squamous Cell,Squamous Cell Carcinoma Of Head And Neck,Lung Squamous Cell Carcinoma,Esophageal Adenocarcinoma,Carcinoma, Ovarian Epithelial,Adenocarcinoma Of Lung

PROVIDER: 2371081 | ecrin-mdr-crc |

REPOSITORIES: ECRIN MDR

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