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Fecal DNA Methylation Test for Colorectal Cancer Screening

ABSTRACT: This is an observational, prospective study using fecal DNA methylation test to define the risk of suffering from advanced adenoma or colorectal cancer (CRC) compared to colonoscopy and fecal immunochemical test (FIT). This study recruits at least 80 participants, including 40 people of healthy controls, 20 people with adenoma, and 20 people with CRC, which were confirmed by colonoscopy. All fecal specimens from participants will be examined by FIT and multi-methylated target gene detection through real-time quantitative methylation-specific PCR (qMSP). The objective of this study is to evaluate the sensitivity and specificity of multi-methylated target PCR compared with the FIT and confirm the examination results through colonoscopy.

DISEASE(S): Colorectal Adenoma,Colorectal Cancer,Colorectal Neoplasms,Adenoma

PROVIDER: 2372684 | ecrin-mdr-crc |

REPOSITORIES: ECRIN MDR

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