Clinical

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A Beta-only IL-2 ImmunoTherapY Study


ABSTRACT: This is a Phase 1/2, multi-center, open-label, dose-escalation and expansion study to evaluate safety and tolerability, PK, pharmacodynamic, and early signal of anti-tumor activity of MDNA11 alone or in combination with a checkpoint inhibitor in patients with advanced solid tumors.

DISEASE(S): Carcinoma,Triple Negative Breast Neoplasms,Carcinoma, Basal Cell,Fallopian Tube Cancer,Acral Melanoma,Mesothelioma,Triple Negative Breast Cancer,Endometrial Neoplasms,Cutaneous Squamous Cell Carcinoma,Lung Neoplasms,Carcinoma, Merkel Cell,Neoplasms,Dmmr Solid Malignant Tumor,Fallopian Tube Neoplasms,Nsclc,Pleural Mesothelioma,Basal Cell Carcinoma,Cancer With A High Tumor Mutational Burden,Mucosal Melanoma,Gastric Cancer,Advanced Solid Tumor,Carcinoma, Renal Cell,Carcinoma, Non-small-cell Lung,Primary Peritoneal Cancer,Solid Tumor, Adult,Gastroesophageal Junction (gej) Cancer,Hepatocellular Carcinoma,Cutaneous Melanoma,Solid Tumor,Non-small Cell Lung Cancer Squamous,Colorectal Cancer (msi-h),Cervical Cancer,Clear Cell Renal Cell Carcinoma,Melanoma,Bladder Cancer,Non-small Cell Lung Cancer Non-squamous,Merkel Cell Carcinoma,Carcinoma, Squamous Cell,Squamous Cell Carcinoma Of Head And Neck,Epithelial Ovarian Carcinoma,Carcinoma, Ovarian Epithelial,Esophageal Cancer,Unresectable Solid Tumor,Msi-h Solid Malignant Tumor,Cancer,Endometrial Carcinoma

PROVIDER: 2392902 | ecrin-mdr-crc |

REPOSITORIES: ECRIN MDR

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