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FIT— Can a Dipstick Test Rule Out Bowel Cancer?

ABSTRACT: See https://www.cancerresearchuk.org/about-cancer/find-a-clinical-trial/a-study-looking-at-a-new-test-called-fit-to-look-for-signs-of-bowel-cancer-nice-fit

DISEASE(S): Colorectal Cancer

PROVIDER: 2418716 | ecrin-mdr-crc |

REPOSITORIES: ECRIN MDR

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Fe-FIT-Diff

Project description:au13-06_fit - Fe-FIT-Diff - FIT (FER-LIKE IRON DEFICIENCY-INDUCED TRANSCRIPTION FACTOR) is a regulator of Fe deficiency responses in the root. FIT is a basic helix-loop-helix protein. Here, we investigated the transcriptome changes in response to Fe deficiency (- Fe) versus the control condition (+ Fe) in wild type, the fit-3 loss of function mutant and in FIT overexpression plants.

2015-02-14 | GSE65934 | GEO

fe-fit-diff_6d-Differential gene expression in A. thaliana roots depending on iron supply and FIT (FER-LIKE IRON DEFICIENCY-INDUCED TRANSCRIPTION FACTOR) abundance

Project description:au15-01_iron-fit - fe-fit-diff_6d - Changes in gene expression profiles between fit knock-out, wild-type and FIT overexpressor seedlings under sufficient iron supply and under iron deficiency. - Col-0, HA-FIT and fit-3.

2016-07-01 | GSE80281 | GEO

fe-fit-diff_6d-Differential gene expression in A. thaliana roots depending on iron supply and FIT (FER-LIKE IRON DEFICIENCY-INDUCED TRANSCRIPTION FACTOR) abundance

2016-07-01 | E-GEOD-80281 | biostudies-arrayexpress

Expression data from FIT-039 or Flavopiridol compound treated HeLa cells

Project description:FIT-039 is a novel antiviral compound. Antiviral mechanism of FIT-039 is the inhibition of the viral transcription through suppression of the CTD phosphorylation of RNA polymerase II. We used microarrays to evaluated the effect of FIT-039 on host cellular transcriptome, compared with Flavopiridol which is an existing pan-specific CDK9 inhibitor. HeLa cells were incubated with FIT-039 or flavopiridol at the concentration of IC80 for 24 hr, and cellular RNAs were collected and subjected to microarray analysis. The solvent DMSO was used as a negative control.

2014-07-08 | E-GEOD-57429 | biostudies-arrayexpress

Expression data from FIT-039 or Flavopiridol compound treated HeLa cells

2014-07-08 | GSE57429 | GEO

CINATRA: Chromosomal Instability and Anti-Tubulin Response Assessment

Project description:See https://www.cancerresearchuk.org/about-cancer/find-a-clinical-trial/a-trial-looking-at-patupilone-for-people-with-advanced-bowel-cancer

| 2420357 | ecrin-mdr-crc

eRAPID cognitive interview study

Project description:See https://www.cancerresearchuk.org/about-cancer/find-a-clinical-trial/a-study-looking-developing-new-questionnaire-about-side-effects-treatment-eRAPID

| 2420361 | ecrin-mdr-crc

Multicentre international study of capecitabine ± bevacizumab as adjuvant treatment of colorectal cancer

Project description:See https://www.cancerresearchuk.org/about-cancer/find-a-clinical-trial/a-trial-looking-at-capecitabine-with-or-without-bevacizumab-for-colorectal-cancer

| 2417882 | ecrin-mdr-crc

FOCUS4: Molecular selection of therapy in colorectal cancer

Project description:See https://www.cancerresearchuk.org/about-cancer/find-a-clinical-trial/a-trial-looking-at-treatments-for-different-types-of-bowel-cancer-focus4

| 2425724 | ecrin-mdr-crc

Anticipated Regret To Increase Colorectal cancer screening (ARTICS)

Project description:See https://www.cancerresearchuk.org/about-cancer/find-a-clinical-trial/a-study-looking-at-attitudes-to-health-and-bowel-screening-in-scotland-artics

| 2423094 | ecrin-mdr-crc

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