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Screening for Colorectal Cancer in Recipients of Kidney Transplants

ABSTRACT: Interventions: 1. Faecal occult blood testing (FOBT). Participants will perform FOBT following enrolment. This involves using a patient kit to sample their own stools for the presence of blood, mailing their testing kit in to a central lab once it is completed. Testing will be conducted once but may involve sampling several stools. 2. Colonoscopy. All participants will also undergo colonoscopy following the completion of FOBT, regardless of the result. This will be performed within a target of 3 months post enrolment. Primary outcome(s): Sensitivity and specificity of faecal occult blood testing for colorectal cancer and colorectal neoplasia, using colonscopy as the gold standard procedure.[One-off screening with both FOBT and colonoscopy, with a completion target of 3 months post enrolment.] Study Design: Purpose: Screening;Duration: Cross-sectional;Selection: Defined population;Timing: Prospective

DISEASE(S): Kidney Transplantation-post Transplant Malignancy,Colorectal Cancer,Cancer-bowel-back Passage (rectum) Or Large Bowel (colon)

PROVIDER: 2453871 | ecrin-mdr-crc |

REPOSITORIES: ECRIN MDR

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First approach on the use of samples from fecal occult blood screening kits for metabolomic analysis. Application in colorectal cancer population.

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