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Capsule endoscopy in the detection of small bowel neoplasias in patients with Lynch syndrome

ABSTRACT: Interventions: Capsule endoscopy will be performed according with standard method: Small bowel preparation with 2 liters of polyethylene glycol (PEG) preparation. At 5 PM on the evening prior to capsule endoscopy patients will begin drinking an 8-ounce glass of the preparation fluid (in the gallon container) every fifteen minutes until all of the liquid is consumed; Overnight fast; Capsule endoscopy (Mirocam) will be swallowed in the day of the exam and pictures will be taken for 12 h and collected in a recorder. The capsule is eliminated in the feces and does not need to be recovered. The images are read in the appropriate software by an experienced physician. Primary outcome(s): To access the prevalence of small bowel neoplasias in patients with Lynch syndrome using capsule endoscopy findings. Patients with relevant findings at capsule endoscopy- tumours or polyps, will be submitted to upper GI endoscopy or double ballon enetroscopy for histological confirmation.[At the time that capsule endoscopy is performed] Study Design: Purpose: Screening;Duration: Cross-sectional;Selection: Defined population;Timing: Prospective

DISEASE(S): Lynch Syndrome (hereditary Nonpolyposis Colorectal Cancer),Small Bowel Neoplasia,Cancer-bowel-small Bowel (duodenum And Ileum)

PROVIDER: 2458177 | ecrin-mdr-crc |

REPOSITORIES: ECRIN MDR

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