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Diagnostic and Prognostic Significance of Serum Neutrophil Gelatinase-Associated Lipocalin in Patients with Colorectal Cancer


ABSTRACT: Interventions: Colon cancer screening; Studies on tissue samples have shown that NGAL expression increases in CRCs and inflammatory bowel diseases. This study is planned to investigate the usability of serum NGAL level as a diagnostic and/or prognostic biomarker, in patients with colorectal cancer. NGAL level was determined through serum samples. Blood was taken from each patient only once, before polypectomy (for the polip group) or surgery (for the cancer group). Primary outcome(s): Diagnostic role of serum NGAL levels on colorectal cancer patients assessed with using Human NGAL/Lipocalin-2 ELISA kit. All colorectal cancer patients serum NGAL levels determined and compared with the other groups (benign colon polyps and healthy individual).[12 months after reciept of all blood samples.] Study Design: Purpose: Diagnosis; Allocation: Non-randomised trial; Masking: Open (masking not used);Assignment: Parallel

DISEASE(S): Colon Cancer,Cancer-bowel-back Passage (rectum) Or Large Bowel (colon)

PROVIDER: 2461212 | ecrin-mdr-crc |

REPOSITORIES: ECRIN MDR

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