Clinical

Dataset Information

0

Effect of early chemotherapy on angiogenesis after laparoscopic resection in colorectal cancer patients


ABSTRACT: Interventions: Drug : Colorectal cancer patients treated with minimally invasive surgery followed by adjuvant FOLFOX chemotherapy were randomly assigned to two groups: the FOLFOX group, FOLFOX on postoperative day (POD) 7-9; the control group, FOLFOX on POD 21. FOLFOX4 chemotherapy: Leucovorin 200 mg/m2 iv over 2 hrs before 5-FU, d1 and 2; 5-FU 400 mg/m2 iv bolus and then 600 mg/m2 iv over 22 hrs, d 1 and d2; Oxaliplatin 85 mg/m2 iv d1 Blood sampling is performed preoperatively, and POD 3, POD 7-9, POD 9-11, POD 21. Primary outcome(s): levels of plasma VEGF, Ang-1, Ang-2, TSP-1 Primary Purpose : Treatment, Intervention Model : Parallel, Blinding/Masking : Open, Allocation : RCT

DISEASE(S): Neoplasms

PROVIDER: 2509659 | ecrin-mdr-crc |

REPOSITORIES: ECRIN MDR

Similar Datasets

| 2622327 | ecrin-mdr-crc
| 2572851 | ecrin-mdr-crc
| 2739106 | ecrin-mdr-crc
| 2614963 | ecrin-mdr-crc
| 2623557 | ecrin-mdr-crc
| 2687922 | ecrin-mdr-crc
| 2616289 | ecrin-mdr-crc
2008-01-12 | GSE8465 | GEO
| 2512693 | ecrin-mdr-crc
| 2101890 | ecrin-mdr-crc