Clinical

Dataset Information

0

Response Prediction of Hyperthermic Intraperitoneal Chemotherapy in Gastro- Intestinal Cancer


ABSTRACT: Patients with gastric or colon cancer with peritoneal carcinomatosis will receive a biopsy of the tumor during their primary curative surgery. The operation is performed according to standard and includes resection of the primary tumor and any metastases and followed by HIPEC (Intraperitoneal hyperthermic chemoperfusion) according to the respective hospital standard. Organoid cultures from the biopsies are established in the research laboratory. Various chemotherapeutic agents are tested on these tumor organoids in the laboratory and the tumor organoids are analyzed in detail with regard to genetic alterations in order to find alterations that can be addressed, if necessary, by means of targeted drugs against peritoneal carcinomatosis.

DISEASE(S): Peritoneal Neoplasms,Gastrointestinal Neoplasms,Carcinoma,Colon Cancer,Gastric Cancer,Intestinal Neoplasms,Peritoneal Carcinomatosis

PROVIDER: 2517 | ecrin-mdr-crc |

REPOSITORIES: ECRIN MDR

Similar Datasets

2015-05-07 | E-GEOD-64392 | biostudies-arrayexpress
2008-01-31 | GSE8657 | GEO
| 2761505 | ecrin-mdr-crc
2023-03-14 | PXD032047 | Pride
2022-06-27 | GSE202454 | GEO
2023-04-19 | E-MTAB-12557 | biostudies-arrayexpress
2015-05-07 | E-GEOD-65253 | biostudies-arrayexpress
2020-07-24 | E-MTAB-9339 | biostudies-arrayexpress
2018-06-30 | E-MTAB-6516 | biostudies-arrayexpress
2015-05-07 | GSE65253 | GEO