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Oxaliplatin combined with melphalan in IHP.

ABSTRACT: Primary objectives: Firstly, determination of the maximum tolerated dose (MTD) , dose limiting toxicity (DLT) and farmacokinetics in IHP with sequential administration of oxaliplatin and melphalan. Primary endpoints: - Determination of the maximum tolerated dose (MTD) , dose limiting toxicity (DLT) and farmacokinetics in IHP with sequential administration of oxaliplatin and melphalan-Determination of phase II doses of oxaliplatin and melphalan.

DISEASE(S): Patients With Isolated Hepatic Metastases Of Histologically Confirmed Colorectal Adenocarcinoma And For The Phase I Study Also Isolated Hepatic Metastases Of All Other Solid Tumors.

PROVIDER: 2520710 | ecrin-mdr-crc |

REPOSITORIES: ECRIN MDR

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