Neo-adjuvant Simvastatin therapy in colorectal cancer
Ontology highlight
ABSTRACT: Primary objectives: To ascertain whether orally delivered Simvastatin affects levels of apoptosis, proliferation and bone morphogenetic protein pathway activation in colorectal cancer in humans.
Primary endpoints: Levels of BMP2 and 4 and phospho-Smad1 in surgical resection specimens.levels of apoptosis and proliferation in surgical resection specimenslevels of angiogenesis in surgical resection specimens
DISEASE(S): Colorectal Neoplasms Malignant,Colorectal Cancer
PROVIDER: 2521817 | ecrin-mdr-crc |
REPOSITORIES: ECRIN MDR
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