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Validation study using molecular and cell culture methods for personalized medicine in various solid tumors like breast cancer,Non small cell lung cancer, Head and Neck cancer and Colorectal cancer

ABSTRACT: Intervention1: Biopsy: The biopsy tissue will be processed to obtain the primary cell line. In the next stage of the study, the cultured primary cell line will be subjected to various chemotherapeutic agents in different concentrations and studied using real time cell analyzer for 5 days to obtain IC50 values. Both the primary cells and biopsy sample will be subjected to microarray, qPCR and proteomics. Control Intervention1: Nil: Nil Primary outcome(s): To validate methodology to establish primary tumor cell line from biopsy samples of cancer patients like breast cancer, NSCLC, Head & Neck, Colorectal.Timepoint: Baseline

DISEASE(S): Pathologically (histologically Or Cytologically) Confirmed Diagnosis Of Solid Tumor (breast, Lung, Colorectal And Head And Neck)

PROVIDER: 2576317 | ecrin-mdr-crc |

REPOSITORIES: ECRIN MDR

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