Clinical

Dataset Information

0

The Effect of Anaesthetic Drugs on Recovery in Patients Undergoing Cancer surgery


ABSTRACT: Intervention1: KETAMINE: Patients will be randomised to receive low dose ketamine infusions @ 0.1 mg/kg/hr + GA + Epidural; ketamine infusion will be started around the time of skin incision Intervention2: DEXMEDETOMIDINE: : Dexmedetomidine IV infusions @ 0.25 mcg/kg/hr + GA + Epidural; dexmedetomidine infusion will be started around the time of skin incision around the time of incision Control Intervention1: NORMAL SALINE: 0.9 % Saline IV infusions @ 5 ml/hr Primary outcome(s): 1.To assess the effect of infusion of a low dose of ketamine and dexmedetomidine infusions vs placebo on the time to passage of flatus in patients undergoing GI malignancy surgeries.Timepoint: Post - Operatively 24 hrs to 72 hrs Study Design: Randomized, Parallel Group, Placebo Controlled Trial Method of generating randomization sequence:Computer generated randomization Method of allocation concealment:Sequentially numbered, sealed, opaque envelopes Blinding and masking:Participant, Investigator and Outcome Assessor Blinded

DISEASE(S): Gastro Intestinal Malignancy Surgeries

PROVIDER: 2582579 | ecrin-mdr-crc |

REPOSITORIES: ECRIN MDR

Similar Datasets

| 2601412 | ecrin-mdr-crc
2007-03-24 | GSE7353 | GEO
2018-12-28 | GSE124410 | GEO
2011-03-31 | E-MEXP-2682 | biostudies-arrayexpress
2023-07-02 | GSE235921 | GEO
2008-06-15 | E-GEOD-7353 | biostudies-arrayexpress
2007-12-01 | GSE8585 | GEO
2024-09-30 | GSE267650 | GEO
| 2295695 | ecrin-mdr-crc
2015-10-01 | PXD002856 | Pride